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Nutrient in Plants Could Kill Cancer Cells, Study Finds

Nutrient in Plants Could Kill Cancer Cells, Study Finds


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Apigenin is abundant in plants and vegetables

Wikimedia Commons

A recently-released study conducted by researchers at Ohio State University suggests that a compound commonly found in plant-based foods such as parsley, celery, and chamomile tea may be an effective nutrient that helps in killing cancer cells. It was previously known that cancer cells are able to prevent a natural process that would cause them to die like normal cells, but this study newly links the compound apigenin, abundant in many fruits and vegetables, to a phenomenon by which proteins in the body re-establish cancer cells’ profiles so that they do die like normal cells.

Ohio State professors Andrea Doseff and Erich Grotewold served as the co-lead authors of the study, and were able to conclude that apigenin binds with approximately 160 proteins in the body and thus produces an apparently beneficial effect in causing the proteins tore-write the cancer cells’ nature so that they become able to die.

Of course, eating fruits and vegetables is far from a foolproof cure for cancer, but this study should reinforce anyone’s faith in the virtues of healthy eating.


Foods, Herbs, and Supplements That Kill Cancer – Safer and More Effective Than Drugs

A diet consisting of a variety of raw fresh vegetables is the best prevention and also a potential cure for cancer, depending on how far the cancer has progressed and how easily the body can digest and properly assimilate nutrition. Berries, grapes, broccoli, leafy greens, sprouts, avocados, red and yellow peppers, red cabbage, dandelion, beets, and many more foods have been proven in numerous scientific studies to not only prevent, but to also destroy, cancer cells. If we did research on every single piece of produce we eat, we’d probably find that most of them, if not all of them, prevent and fight cancer in some way or another. This is what the modern diet is missing, fresh raw produce. Early humans ate pounds of it a day, all day, every day. Whether you have cancer now, or are just trying to prevent it, cut out the refined and processed foods, and eat more produce.

Herbs and Spices

Garlic, oregano, cloves, cayenne pepper, cinnamon, and ginger have been shown in multiple studies to fight cancer. Spice up your meals, especially those big salads. Fresh raw produce works synergistically with herbs and spices. In other words, the combination of garlic, oregano, and a bunch of vegetables is more powerful than garlic and/or oregano alone. Make big salads with lots of vegetables and add in fresh herbs and spices.Speaking of combinations, turmeric and black pepper make for a powerful cancer-killing duo. Most of you have heard of the incredible benefits of turmeric and it’s cancer-killing properties. Turmeric is known to actually outperform many pharmaceutical drugs for various diseases. The only problem with turmeric is that the beneficial component to which all the hoopla is about, curcumin, is not easily absorbed by the body. Black pepper contains piperine, a chemical with powerful antioxidant properties. Pepper and turmeric together allow the body to absorb more turmeric. Reports range from a 200% increase to over 2,000%! It’s no coincidence that two of the main ingredients in curry powder are black pepper and turmeric. Come to think of it, ginger and cinnamon, two other powerhouse herbs known to fight cancer, are also almost always found in curry spice blends as well. It’s no wonder…

Herbal Supplements, Vitamins, and Minerals

Getting a wide range of vitamins and minerals should be easy when you’re eating lots of produce, but it’s not always that simple. Our soil is so degraded, even organic produce doesn’t have the nutrition it used to have. If you cannot grow your own produce in the most optimum conditions with the best soil, we recommend a primarily food-based nutrition powder from a source you know and trust. That’s not “whole food sourced” we mean actual food, like rose hips, lemon peels, chlorella, etc. And when these nutrition formulas are done right, the enzymes are left intact. There are a ton of herbal tinctures, extracts, and other supplements that kill cancer cells. Echinacea, oil of oregano, clove oil, goldenseal, barberry, astragalus, pau d’arco, red clover, and skullcap are a few of the many plant based herbal supplements that kill cancer cells. Study after study shows that many of the right plants and plant extracts have more power to kill off cancer cells than conventional treatments. Wormwood is a very powerful herb that is often used to kill parasites and Candida. Wormwood, more specifically, wormwood extract, kills cancer cells.

Kill 98% Of All Cancer Cells In Less Than 24 Hours

A new study shows that a derivative of the wormwood plant, artemesinin, turns deadly in the presence of iron. Breast cancer cells have high levels of iron. When artemesinin senses these higher than usual levels of iron, it destroys the cancer cells with little damage to the surrounding healthy cells. This results in an herbal killing machine that killed 98% of the breast cancer cells present within 16 hours! Although this study is in its first phase in a lab with petri dishes, artemesinin tablets are “widely and successfully” used to fight malaria for the same reason, the parasite responsible for malaria uptakes a large amount of iron, just like the breast cancer cells. Artemesinin zeros in on the iron and destroys the parasite.Wormwood is known to be one of the best herbs for killing a number of parasites, and it is anti-microbial and anti-fungal, making wormwood a great addition for people who need to heal their gut.

Check out How to Make Your Own Nutrition Formula here. Also, see the sources below for salad recipes, more nutrition information, and the infamous Budwig Protocol. If you’ve had cancer and have undergone chemotherapy, be sure to read Bullet Proof Your Immune System & Detoxify From Chemotherapy.


Venom from honeybees found to kill aggressive breast cancer cells

Using the venom from 312 honeybees and bumblebees in Perth Western Australia, Ireland and England, Dr Ciara Duffy from the Harry Perkins Institute of Medical Research and The University of Western Australia, tested the effect of the venom on the clinical subtypes of breast cancer, including triple-negative breast cancer, which has limited treatment options.

Results published in the journal npj Precision Oncology revealed that honeybee venom rapidly destroyed triple-negative breast cancer and HER2-enriched breast cancer cells.

Dr Duffy said the aim of the research was to investigate the anti-cancer properties of honeybee venom, and a component compound, melittin, on different types of breast cancer cells.

"No-one had previously compared the effects of honeybee venom or melittin across all of the different subtypes of breast cancer and normal cells.

"We tested honeybee venom on normal breast cells, and cells from the clinical subtypes of breast cancer: hormone receptor positive, HER2-enriched, and triple-negative breast cancer.

"We tested a very small, positively charged peptide in honeybee venom called melittin, which we could reproduce synthetically, and found that the synthetic product mirrored the majority of the anti-cancer effects of honeybee venom," Dr Duffy said.

"We found both honeybee venom and melittin significantly, selectively and rapidly reduced the viability of triple-negative breast cancer and HER2-enriched breast cancer cells.

"The venom was extremely potent," Dr Duffy said.

A specific concentration of honeybee venom can induce 100% cancer cell death, while having minimal effects on normal cells.

"We found that melittin can completely destroy cancer cell membranes within 60 minutes."

Melittin in honeybee venom also had another remarkable effect within 20 minutes, melittin was able to substantially reduce the chemical messages of cancer cells that are essential to cancer cell growth and cell division.

"We looked at how honeybee venom and melittin affect the cancer signalling pathways, the chemical messages that are fundamental for cancer cell growth and reproduction, and we found that very quickly these signalling pathways were shut down.

"Melittin modulated the signalling in breast cancer cells by suppressing the activation of the receptor that is commonly overexpressed in triple-negative breast cancer, the epidermal growth factor receptor, and it suppressed the activation of HER2 which is over-expressed in HER2-enriched breast cancer," she said.

Western Australia's Chief Scientist Professor Peter Klinken said "This is an incredibly exciting observation that melittin, a major component of honeybee venom, can suppress the growth of deadly breast cancer cells, particularly triple-negative breast cancer.

"Significantly, this study demonstrates how melittin interferes with signalling pathways within breast cancer cells to reduce cell replication. It provides another wonderful example of where compounds in nature can be used to treat human diseases," he said.

Dr Duffy also tested to see if melittin could be used with existing chemotherapy drugs as it forms pores, or holes, in breast cancer cell membranes, potentially enabling the entry of other treatments into the cancer cell to enhance cell death.

"We found that melittin can be used with small molecules or chemotherapies, such as docetaxel, to treat highly-aggressive types of breast cancer. The combination of melittin and docetaxel was extremely efficient in reducing tumour growth in mice."

Dr Duffy's research was conducted as part of her PhD undertaken at Perth's Harry Perkins Institute of Medical Research at the Cancer Epigenetics laboratory overseen by A/Prof. Pilar Blancafort. "I began with collecting Perth honeybee venom. Perth bees are some of the healthiest in the world.

"The bees were put to sleep with carbon dioxide and kept on ice before the venom barb was pulled out from the abdomen of the bee and the venom extracted by careful dissection," she said.

While there are 20,000 species of bees, Dr Duffy wanted to compare the effects of Perth honeybee venom to other honeybee populations in Ireland and England, as well as to the venom of bumblebees.

"I found that the European honeybee in Australia, Ireland and England produced almost identical effects in breast cancer compared to normal cells. However, bumblebee venom was unable to induce cell death even at very high concentrations.

One of the first reports of the effects of bee venom was published in Nature in 1950, where the venom reduced the growth of tumours in plants. However, Dr Duffy said it was only in the past two decades that interest grew substantially into the effects of honeybee venom on different cancers.

In the future, studies will be required to formally assess the optimum method of delivery of melittin, as well as toxicities and maximum tolerated doses.


Herbs and Spices

Related:

Speaking of combinations, turmeric and black pepper make a powerful cancer-killing duo. Most of you have heard of the incredible benefits of turmeric and it’s cancer-killing properties. Turmeric is known to actually outperform many pharmaceutical drugs for various diseases. The only problem with turmeric is that the beneficial component to which all the hoopla is about, curcumin, is not easily absorbed by the body. Black pepper contains piperine, a chemical with powerful antioxidant properties. Pepper and turmeric together inhibit the growth of cancer cells without destroying healthy cells.

When people eat a considerable amount of turmeric, within an hour, there’s a slight increase of curcumin in the blood, but the liver actually tries to get rid of it. When taken with a small amount of black pepper, the curcumin levels skyrocket. Reports range from a 200% increase to over 2,000%! It’s no coincidence that two of the main ingredients in curry powder are black pepper and turmeric. Come to think of it, ginger and cinnamon, two other powerhouse herbs, are also almost always found in curry spice blends as well. It’s no wonder…

Just like produce, raw herbs and spices are best (as opposed to powdered and processed). Cook with them all you like, but before eating a cooked meal, try throwing in some more flavor with freshly grated, crushed, or ground spices. This practice will not only increase your health, it will radically improve the taste of your food as well.

It should be noted that while I am a fan of whole foods, there are extracts and other supplement forms of foods that can be much more powerful for certain conditions and ailments.


Herbs and Spices

Related:

Speaking of combinations, turmeric and black pepper make a powerful cancer-killing duo. Most of you have heard of the incredible benefits of turmeric and it’s cancer-killing properties. Turmeric is known to actually outperform many pharmaceutical drugs for various diseases. The only problem with turmeric is that the beneficial component to which all the hoopla is about, curcumin, is not easily absorbed by the body. Black pepper contains piperine, a chemical with powerful antioxidant properties. Pepper and turmeric together inhibit the growth of cancer cells without destroying healthy cells.

When people eat a considerable amount of turmeric, within an hour, there’s a slight increase of curcumin in the blood, but the liver actually tries to get rid of it. When taken with a small amount of black pepper, the curcumin levels skyrocket. Reports range from a 200% increase to over 2,000%! It’s no coincidence that two of the main ingredients in curry powder are black pepper and turmeric. Come to think of it, ginger and cinnamon, two other powerhouse herbs, are also almost always found in curry spice blends as well. It’s no wonder…

Just like produce, raw herbs and spices are best (as opposed to powdered and processed). Cook with them all you like, but before eating a cooked meal, try throwing in some more flavor with freshly grated, crushed, or ground spices. This practice will not only increase your health, it will radically improve the taste of your food as well.

It should be noted that while I am a fan of whole foods, there are extracts and other supplement forms of foods that can be much more powerful for certain conditions and ailments.


Honeybee venom destroyed breast cancer cells, study finds

Scientists have been working for years to save the world's honeybee population, and now there may be more of an incentive. According to a study, honeybee venom rapidly kills breast cancer cells.

PERTH, Australia - Venom from honeybees rapidly destroyed triple-negative breast cancer, a type of cancer that has limited treatment options, and HER2-enriched breast cancer cells, according to a study published in the journal npj Precision Oncology.  Using the venom from over 300 honeybees and bumblebees in England, Ireland and Perth, Western Australia, Dr. Ciara Duffy from the Harry Perkins Institute of Medical Research and The University of Western Australia, tested the effect of the venom on the clinical subtypes of breast cancer, according to the news release.

"The venom was extremely potent," Duffy said in the release.

The study investigated the anti-cancer properties of the venom in honeybees and melittin, the �tive component of honeybee venom” according to the published study on different types of breast cancer cells.

Melittin and honeybee venom were studied for their anti-cancer properties and showed they decreased the viability of triple-negative breast cancer cells and HER2-enriched breast cancer cells, Dr.Ciara Duffy said in her study. (iStock)

"We found both honeybee venom and melittin significantly, selectively and rapidly reduced the viability of triple-negative breast cancer and HER2-enriched breast cancer cells,” Duffy said in the release.

Duffy explained in the release of the compound, melittin, also had positive results. "We tested a very small, positively charged peptide in honeybee venom called melittin, which we could reproduce synthetically, and found that the synthetic product mirrored the majority of the anti-cancer effects of honeybee venom.”

Duffy said the study showed melittin not only destroyed cancer cells but also reduced the cancer cells’ chemical messages that enable the cancer to divide and proliferate within 20 minutes. "We found that melittin can completely destroy cancer cell membranes within 60 minutes."

"We looked at how honeybee venom and melittin affect the cancer signaling pathways, the chemical messages that are fundamental for cancer cell growth and reproduction, and we found that very quickly these signaling pathways were shut down.” Duffy said in the release.

The melittin was also tested to see if it could be used in conjunction with current chemotherapy drugs. Melittin forms pores in the cancer cell membranes which could potentially help the entry of other treatments into the cancer cell, to help destroy the cancer, according to the press release.

"We found that melittin can be used with small molecules or chemotherapies, such as docetaxel, to treat highly-aggressive types of breast cancer. The combination of melittin and docetaxel was extremely efficient in reducing tumor growth in mice."

Professor Peter Klinken, Western Australia&aposs chief scientist, said in the release, "This is an incredibly exciting observation that melittin, a major component of honeybee venom, can suppress the growth of deadly breast cancer cells, particularly triple-negative breast cancer.”

Klinken also said, “It provides another wonderful example of where compounds in nature can be used to treat human diseases.”

Duffy also stated the type of bee was particular to her findings. "I found that the European honeybee in Australia, Ireland and England produced almost identical effects in breast cancer compared to normal cells. However, bumblebee venom was unable to induce cell death even at very high concentrations.”

The release said future studies are needed to formally assess the best method of providing melittin, as well as maximum tolerated doses and potential toxicities.


Honeybee venom kills aggressive breast cancer cells, study shows

Could honeybees hold the key to treating an aggressive form of breast cancer?

A new study out of Australia found that honeybee venom rapidly killed the cells for triple-negative breast cancer, a type of breast cancer that currently has few treatment options.

“It provides another wonderful example of where compounds in nature can be used to treat human diseases,” said Western Australia Chief Scientist Professor Peter Klinken in a Harry Perkins Institute of Medical Research press release.

The research, published in Nature Precision Oncology Tuesday, was led by Dr. Ciara Duffy of the Harry Perkins Institute of Medical Research and the University of Western Australia.

Perkins and @uwanews researcher Dr Ciara Duffy has found that honeybee venom can induce cancer cell death in hard to treat triple-negative breast cancer with minimal effect on healthy cells.
Learn more at https://t.co/6CeDsCZklZ

— The Perkins (@PerkinsComms) September 2, 2020

As far back as 1950, bee venom was shown to kill tumors in plants. It has also been shown to work against other cancers like melanoma, BBC News explained. However, Duffy said in the press release that this was the first time honeybee venom had been tested against every type of breast cancer cell, as well as normal breast cells.

Duffy and her team tested both the venom itself and a synthetic version of a compound in the venom called melittin. They found that both were effective against triple-negative breast cancer and HER2-enriched breast cancer cells. In fact, a certain concentration of honeybee venom could kill 100 percent of cancer cells without seriously impacting healthy ones.

“The venom was extremely potent,” Duffy said.

Duffy explained to Australia’s ABC News how the melittin worked.

“What melittin does is it actually enters the surface, or the plasma membrane, and forms holes or pores and it just causes the cell to die,” Duffy said.

The researchers also found that the melittin interfered with the cancer cells’ messaging system, which is essential for the cancer to reproduce and grow.

The fact that melittin makes holes in the cancer cells actually means it could potentially be paired with existing chemotherapies that would enter the cancer cells through the openings it carved and kill them. Duffy found this treatment strategy worked to shrink tumors in mice.

However, outside scientists cautioned that there is a big difference between killing cancer in a lab and successfully treating it in humans.

“It’s very early days,” Garvan Institute of Medical Research in Sydney associate professor Alex Swarbrick told BBC News. “Many compounds can kill a breast cancer cell in a dish or in a mouse. But there’s a long way to go from those discoveries to something that can change clinical practice.”

Duffy agreed that more research had to be done before the melittin could be used on human patients.

“There’s a long way to go in terms of how we would deliver it in the body and, you know, looking at toxicities and maximum tolerated doses before it ever went further,” she told ABC News.

For the study, Duffy gathered venom from 312 honeybees and bumblebees in Perth, Western Australia England and Ireland.

“Perth bees are some of the healthiest in the world,” she said.

She found that the national origin of the honeybees did not alter their venom’s impact on the cancer. The bumblebee venom, however, had no cancer-killing powers.


Substance in breast milk kills cancer cells, study suggests

A substance found in breast milk can kill cancer cells, reveal studies carried out by researchers at Lund University and the University of Gothenburg, Sweden.

Although the special substance, known as HAMLET (Human Alpha-lactalbumin Made LEthal to Tumour cells), was discovered in breast milk several years ago, it is only now that it has been possible to test it on humans. Patients with cancer of the bladder who were treated with the substance excreted dead cancer cells in their urine after each treatment, which has given rise to hopes that it can be developed into medication for cancer care in the future.

HAMLET was discovered by chance when researchers were studying the antibacterial properties of breast milk. Further studies showed that HAMLET comprises a protein and a fatty acid that are both found naturally in breast milk. So far, however, it has not been proven that the HAMLET complex is spontaneously formed in the milk. It is speculated, however, that HAMLET can form in the acidic environment of the babies´ stomachs. Laboratory experiments have shown that HAMLET kills 40 different types of cancer, and the researchers are now going on to study its effect on skin cancer, tumours in the mucous membranes and brain tumours. Importantly, HAMLET kills only cancer cells and does not affect healthy cells.

Studying the integration of the substance

Researchers at the University of Gothenburg are focusing on how HAMLET can be taken up into tumour cells. The researchers, Roger Karlsson, Maja Puchades and Ingela Lanekoff, are attempting to gain an in-depth understanding of how the substance interacts with cell membranes, and their findings were recently published in the journal PLoS One.

Story Source:

Materials provided by University of Gothenburg. Note: Content may be edited for style and length.


Camomile Tea Could Fight Superpower Of Cancer Cells, Study Suggests

A compound that can be found in parsley, celery and camomile tea could halt the spread of cancer cells, scientists claim.

Unlike normal cells, cancer cells have a 'superpower' to escape death and can inhibit the processes that should cause them to die on a regular basis.

However, in a statement, researchers from Ohio State University explain that ‘apigenin’, which can be found in certain plant-based foods, can take away cancer this ‘superpower’.

Scientists suggest that apigenin essentially re-educates cancer cells into normal cells that will die as scheduled.

Parsley, celery and camomile tea are the most common sources of apigenin, but it is also found in many fruits and vegetables common in a Mediterranean diet.

"We know we need to eat healthfully, but in most cases we don't know the actual mechanistic reasons for why we need to do that," said Andrea Doseff, associate professor of internal medicine and molecular genetics at Ohio State and a co-lead author of the study, in a statement.

"We see here that the beneficial effect on health is attributed to this dietary nutrient affecting many proteins. In its relationship with a set of specific proteins, apigenin re-establishes the normal profile in cancer cells. We think this can have great value clinically as a potential cancer-prevention strategy."

The research appears in the journal Proceedings of the National Academy of Sciences.

Here are more foods that researchers believe could help fight cancer


Reviewing Nigerian medicinal plants for anti-cancer properties

The study was comprehensive in that it did not look at just one or two medicinal plants, but 31 in total. The researchers wanted to determine which plants had the most potent cytotoxic activity on rhabdomyosarcoma (RD) cancer cell lines. To determine this, they used an MTT assay and a brine shrimp lethality assay (BSLA), a test that determines the toxicity of a substance based on how effectively it kills brine shrimps.

Rhabdomyosarcoma is a type of cancer that affects the soft tissue and is known to affect people below 20 years old. It rarely occurs in the U.S. (about five cases per million children in a year), but in the researchers’ home country, it is one of the leading cause of death among children.

The researchers discovered that among the extracts tested, those of Macaranga barteri and Calliandra portoricensis had the most significant cytotoxic activity on both the RD cell line and the brine shrimps. When examined further, they found that the dichloromethane fraction of M. barteri and the ethyl acetate fraction of C. portoricensis were more effective than cyclophosphamide, a chemotherapy drug, by up to six and four times respectively.

Furthermore, both extracts exhibited a high selectivity index, which means that unlike normal chemo drugs, they acted against cancer cells while sparing healthy cells.

The researchers noted that while 11 plants showed cytotoxic activity in their research, only those two exceeded the effects of cyclophosphamide as a cancer cell killer.